Monthly Archives: March 2018

Adderall Generic vs Brand – Which is Best and Why

Adderall Generic vs Brand – Which is Best and Why?

Paying full price for Adderall is an experience no one wants to go through.  In 2002 the first generic was introduced for Adderall IR (Instant Release) by Barr Laboratories Inc (1).  Since then a number of new generics have popped up on the market.  I’m going to present you with the facts about generics and provide a list of the companies approved to manufacture generic Adderall.  Without further ado let’s compare Adderall generic vs brand!

It is very important to keep track of which generic works best for you as the absorption between the generic and the name brand can fluctuate as much as 10% and still be considered bioequivalent (in the United States per the FDA) (2).  

Studies have been done comparing the absorption of generics vs name brand drugs and have identified on average a 4.35% fluctuation in the absorption between them (3).

Adderall XR (Extended Release) Generic Brands

Shire, TEVA, and BARR generics all use the original formula.  You are taking a risk with the others in terms of “being just like the original”.

Manufacturer Approval Date
*SHIRE DEVELOPMENT INC Oct 11, 2001
ACTAVIS ELIZABETH LLC Jun 22, 2012
IMPAX LABORATORIES INC Feb 16, 2016
*TEVA PHARMACEUTICALS USA INC Apr 29, 2013
*BARR LABORATORIES INC Feb 12, 2013

* Shire is permitted to sell the original formula.

Adderall IR (Instant Release) Generic Brands

There are currently eleven manufacturer’s approved to sell generic instant release Adderall.  Only TEVA uses the original formula.

Manufacturer Approval Date
*TEVA (BARR LABORATORIES INC) Feb 11, 2002
SANDOZ INC Jun 14, 2002
EPIC PHARMA LLC Jun 19, 2002
SUN PHARMACEUTICAL INDUSTRIES INC Sep 9, 2003
SPECGX LLC Oct 7, 2003
AUROLIFE PHARMA LLC Nov 27, 2013
MYLAN PHARMACEUTICALS INC Nov 10, 2015
ACTAVIS ELIZABETH LLC Feb 5, 2016
ALVOGEN MALTA OPERATIONS LTD Jul 28, 2017
NESHER PHARMACEUTICALS USA LLC Oct 31, 2017
SUNRISE PHARMACEUTICAL INC Dec 28, 2017

* Only TEVA uses the original formula

Adderall Instant Release Best Generic – TEVA (aka BARR Laboratories)

Teva is by far the best because they use the original formula.  The first picture below shows a 20 mg tablet and the second a 30 mg tablet (4).

Wondering why the label author is listed as “Barr Laboratories Inc.” and I said this is Teva?  That’s because Teva acquired Barr Laboratories Inc. in 2008 (5)

Adderall Generic vs Brand - Which is Best and Why

References:

  1. “National Drug Code Amphetamine Search Results”National Drug Code Directory. United States Food and Drug Administration. Archived from the original on 16 December 2013. Retrieved 16 December 2013.
  2. Center for Drug Evaluation and Research (2003). “Guidance for Industry: Bioavailability and Bioequivalence Studies for Orally Administered Drug Products — General Considerations” (PDF). United States Food and Drug Administration.
  3. Comparing generic and innovator drugs: a review of 12 years of bioequivalence data from the United States Food and Drug Administration 2009 Oct;43(10):1583-97. doi: 10.1345/aph.1M141. Epub 2009 Sep 23.
  4. Identify or Search for a Pill. National Laboratory of Medicine.
  5. “Teva Completes Acquisition of Barr”. Drugs.com. Retrieved 31 October 2011.